Ay: Mayıs 2023

The MMPI profile traits of borderline personality disorder.

7 Mayıs 2023 Doğan ŞAHİN 0

Objectives: Distinctive, effective and systematic psychological test methods to be used to di-agnose, treat and research borderline personality disorder (BPD) need to be developed and adminis-tered. This study investigates the MMPI profile characteristics of BPD to determine the original pro-file of BPD. Methods: This comparative and descriptive study was conducted in the psychiatric clinic of a university hospital from 2000 to 2013. Its sample consisted of 51 patients with BPD, 31 patients with BPD and comorbid personality disorders and 31 patients with no psychiatric diagnosis according to DSM-IV. The MMPI was administered individually to the subjects diagnosed with BPD before the start of treatment and in face-to-face interviews with all participants. The study used chi-square, inde-pendent sample t-test, and the differences between the patient and control groups’ MMPI subtests were examined using logistic regression.

Noradrenergic and serotoninergic depression?

7 Mayıs 2023 Doğan ŞAHİN 0

The aim of this study was to test the hypothesis of noradrenergic and serotoninergic depressive subtypes. For this purpose, the correlation between three variables was investigated: urinary 3-methoxy- 4-hydroxyphenylglycol (MHPG), dexamethasone suppression test (DST), and clinical response profiles to clomipramine and maprotiline, the effects of which are relatively selective on the uptake of noradrenalin (NA) and 5-hydroxytriptamine (5HT). Our results showed no correlation between these measures. Therefore, the hypothesis of two subtypes of depression was not supported. The only significant finding in this study was the obvious decrease in MHPG excretion during the antidepressant treatment in the group with high pretreatment MHPG.